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Aguirre Lab for ​Pancreatic Cancer Research​

We are a basic and translational oncology laboratory with a mission to improve the diagnosis and treatment of pancreatic cancer. 
We use genomics, functional genetic screening, molecular and cell biology approaches to:

  • Understand the genetics and biology of pancreatic cancer and other RAS-driven cancers
  • Discover and mechanistically define new therapeutic strategies that can be validated in preclinical cancer models
  • Translate laboratory findings into new clinical trials

Our research team is comprised of bench scientists, computational biologists and clinicians who work together with a common goal to improve the care of pancreatic cancer patients.


Recent Aguirre Lab News

2025-05 Congratulations to Dan Gui on being selected as a 2025 Lubin Family Foundation Scholar!

​2025-05 Best of luck to James, who after two years in the lab as a research technician is leaving to start medical school at the University of Pittsburgh in the fall.

2025-04 Several Aguirre lab members, including Josh Choe and Panot "Boom" Sainamthip, presented their work at the 2025 AACR Annual Meeting in Chicago.

2025-04 We are excited to welcome Jon DeLiberty, our newest postdoctoral fellow, to the lab!

2025-01 Congratulations to Andy on becoming a Co-Director for the newly launched DFCI Center for RAS Therapeutics! Read coverage by DFCI, Cancer Discovery News, Inside Precision Medicine, and Nature Reviews Drug Discovery.

2024-12 Best of luck to visiting scientist Ji-Won​ Kim as he returns to Seoul National University Bundang Hospital. It was a pleasure hosting you in the lab! 

Read more here


Check out the Aguirre Lab's feature in "An Army of Investigators" and in "Pancreatic Cancer Survivors Series- Year Three" from the Let's Win! Pancreatic Cancer YouTube channel below: 

Watch "An Army of Investigators -- Pancreatic Cancer Doctors and Researchers”

Watch "Let’s Win! Pancreatic Cancer Survivors Series—Year Three"