Aguirre Lab for Pancreatic Cancer Research
We are a basic and translational oncology laboratory with a mission to improve the diagnosis and treatment of pancreatic cancer.
We use genomics, functional genetic screening, molecular and cell biology approaches to:
- Understand the genetics and biology of pancreatic cancer and other RAS-driven cancers
- Discover and mechanistically define new therapeutic strategies that can be validated in preclinical cancer models
- Translate laboratory findings into new clinical trials
Our research team is comprised of bench scientists, computational biologists and clinicians who work together with a common goal to improve the care of pancreatic cancer patients.
Recent Aguirre Lab News
2025-05 Congratulations to Dan Gui on being selected as a 2025 Lubin Family Foundation Scholar!
2025-05 Best of luck to James, who after two years in the lab as a research technician is leaving to start medical school at the University of Pittsburgh in the fall.
2025-04 Several Aguirre lab members, including Josh Choe and Panot "Boom" Sainamthip, presented their work at the 2025 AACR Annual Meeting in Chicago.
2025-04 We are excited to welcome Jon DeLiberty, our newest postdoctoral fellow, to the lab!
2025-01 Congratulations to Andy on becoming a Co-Director for the newly launched DFCI Center for RAS Therapeutics! Read coverage by DFCI, Cancer Discovery News, Inside Precision Medicine, and Nature Reviews Drug Discovery.
2024-12 Best of luck to visiting scientist Ji-Won Kim as he returns to Seoul National University Bundang Hospital. It was a pleasure hosting you in the lab!
Read more here
Check out the Aguirre Lab's feature in "An Army of Investigators" and in "Pancreatic Cancer Survivors Series- Year Three" from the Let's Win! Pancreatic Cancer YouTube channel below:
Watch "An Army of Investigators -- Pancreatic Cancer Doctors and Researchers”
Watch "Let’s Win! Pancreatic Cancer Survivors Series—Year Three"
