Aguirre Lab for Pancreatic Cancer Research
We are a basic and translational oncology laboratory with a mission to improve the diagnosis and treatment of pancreatic cancer.
We use genomics, functional genetic screening, molecular and cell biology approaches to:
- Understand the genetics and biology of pancreatic cancer and other RAS-driven cancers
- Discover and mechanistically define new therapeutic strategies that can be validated in preclinical cancer models
- Translate laboratory findings into new clinical trials
Our research team is comprised of bench scientists, computational biologists and clinicians who work together with a common goal to improve the care of pancreatic cancer patients.
Recent Aguirre Lab News
2025-08 Best of luck to Kazuki Takahashi, who is returning to Tokyo, Japan to continue his career at Daiichi Sankyo as Senior Scientist.
2025-08 Congratulations to our summer student, Karen Khela, who gave a terrific oral presentation on her research at the YES for CURE event.
2025-06 After three years in the lab, Laleh Abbassi is starting a clinical fellowship in Laboratory Genetics and Genomics (LGG) at Baylor College of Medicine. Congrats, Laleh!
2025-05 Congratulations to Dan Gui on being selected as a 2025 Lubin Family Foundation Scholar!
2025-05 Best of luck to James, who after two years in the lab as a research technician is leaving to start medical school at the University of Pittsburgh in the fall.
2025-04 Several Aguirre lab members, including Josh Choe and Panot "Boom" Sainamthip, presented their work at the 2025 AACR Annual Meeting in Chicago.
2025-04 We are excited to welcome Jon DeLiberty, our newest postdoctoral fellow, to the lab!
2025-01 Congratulations to Andy on becoming a Co-Director for the newly launched DFCI Center for RAS Therapeutics! Read coverage by DFCI, Cancer Discovery News, Inside Precision Medicine, and Nature Reviews Drug Discovery.
Read more here
Check out the Aguirre Lab's feature in the videos below:
Watch "Dana-Farber Cancer Institute Awards the Hale Family Its Highest Honor"
Watch "An Army of Investigators -- Pancreatic Cancer Doctors and Researchers”
Watch "Let’s Win! Pancreatic Cancer Survivors Series—Year Three"
