Baca Lab News
6.5.26 - Congrats to Paulo on a successful dissertation qualifying exam!
6.3.26 - Welcome Siyan!
6.1.26 - Rashad presents at ASCO 2026 on inferring NECTIN4 expression with epigenomic liquid biopsy to predict response to EV in bladder cancer.
6.1.26 - Weiwei presents at ASCO 2026 on prostate cancer subtyping based on cfDNA fragmentation signatures
5.23.26 - Gun presents on liquid bx in prostate cancer at ISLB
5.1.26 - David Lee’s piece out in Nature Cancer on using DNA methylation profiling to link environmental exposures to early-onset colorectal cancer
4.30.26 - Surya, Gun, Paulo presenting at AI in Health Frontiers meeting in Boston
4.10. 26 - Perspective piece in JCO on functional liquid biopsy in precision oncology https://pubmed.ncbi.nlm.nih.gov/41512214/
4.8.26 - Preprint on characterizing resistance to tarlatamab with liquid biopsy and mouse modeling https://pubmed.ncbi.nlm.nih.gov/41993528/
4.6.26: Karl and Marc’s preprint on pancreatic cancer subtyping with liquid biopsy https://pubmed.ncbi.nlm.nih.gov/42006774/
3.20.26 - Congrats to Razane for matching in Pediatrics at Pitt!
3.16.26 - Gun presents at the NCI Liquid Biopsy interest group meeting on inferring gene expression in cancer from circulating chromatin
3.2.26 - Rashad presents on predicting cell surface target expression in NEPC using cfChIP-seq at ASCO GU26
2.27.26 - Ze Zhang receives a Scholar in Training Award to present at AACR on urine cfDNA methylation signatures to detect urinary tract cancers
2.23.26 - Sylvan presents our lab’s work at the DFCI Seminars in Oncology series
2.19. 26 - Preprint on integrated inference of cancer gene expression from cell-free plasma chromatin https://pubmed.ncbi.nlm.nih.gov/41756975/
1.7.26 - Welcome, Surya!
12.30.25 - Preprint on SNAP pipeline for cfChIP-seq data analysis:https://pubmed.ncbi.nlm.nih.gov/41509217/
11.13.25 - Alexis and Gary’s preprint out on inferring enhancer RNA expression from cfDNA: https://pubmed.ncbi.nlm.nih.gov/41279066/
6.3.26 - Welcome Siyan!
6.1.26 - Rashad presents at ASCO 2026 on inferring NECTIN4 expression with epigenomic liquid biopsy to predict response to EV in bladder cancer.
6.1.26 - Weiwei presents at ASCO 2026 on prostate cancer subtyping based on cfDNA fragmentation signatures
5.23.26 - Gun presents on liquid bx in prostate cancer at ISLB
5.1.26 - David Lee’s piece out in Nature Cancer on using DNA methylation profiling to link environmental exposures to early-onset colorectal cancer
4.30.26 - Surya, Gun, Paulo presenting at AI in Health Frontiers meeting in Boston
4.10. 26 - Perspective piece in JCO on functional liquid biopsy in precision oncology https://pubmed.ncbi.nlm.nih.gov/41512214/
4.8.26 - Preprint on characterizing resistance to tarlatamab with liquid biopsy and mouse modeling https://pubmed.ncbi.nlm.nih.gov/41993528/
4.6.26: Karl and Marc’s preprint on pancreatic cancer subtyping with liquid biopsy https://pubmed.ncbi.nlm.nih.gov/42006774/
3.20.26 - Congrats to Razane for matching in Pediatrics at Pitt!
3.16.26 - Gun presents at the NCI Liquid Biopsy interest group meeting on inferring gene expression in cancer from circulating chromatin
3.2.26 - Rashad presents on predicting cell surface target expression in NEPC using cfChIP-seq at ASCO GU26
2.27.26 - Ze Zhang receives a Scholar in Training Award to present at AACR on urine cfDNA methylation signatures to detect urinary tract cancers
2.23.26 - Sylvan presents our lab’s work at the DFCI Seminars in Oncology series
2.19. 26 - Preprint on integrated inference of cancer gene expression from cell-free plasma chromatin https://pubmed.ncbi.nlm.nih.gov/41756975/
1.7.26 - Welcome, Surya!
12.30.25 - Preprint on SNAP pipeline for cfChIP-seq data analysis:https://pubmed.ncbi.nlm.nih.gov/41509217/
11.13.25 - Alexis and Gary’s preprint out on inferring enhancer RNA expression from cfDNA: https://pubmed.ncbi.nlm.nih.gov/41279066/
9.25.25 - Sylvan joins a discussion panel on cancer biomarkers at the World CDx Summit
8.5.25 - Welcome, David Jin!
7.9. 25 - Karl and Rashad’s paper published in NPJ Precision Oncology on detecting squamous differentiation of prostate cancer with liquid biopsy.
8.5.25 - Welcome, David Jin!
7.9. 25 - Karl and Rashad’s paper published in NPJ Precision Oncology on detecting squamous differentiation of prostate cancer with liquid biopsy.
4.28.25 - Ze presents his pipeline for cfChIP-seq data analysis at AACR 2025.
4.25.25 - Surya presents his work on rare variant germline genetics at the American Physiologic Summit 2025.
4.25.25 - Surya presents his work on rare variant germline genetics at the American Physiologic Summit 2025.
3.7.25 - Welcome, Yukun!
2.18.25 - Rashad receives an ASCO Merit Award for his ASCO GU25 poster on HIF2α activity and sarcomatoid differentiation in RCC
10.25.24 - The Baca Lab receives the Prostate Cancer Foundation / American Cancer Society Young Investigator Award
10.22.24 - Welcome to rotating HMS PhD students Chris, Harlan, and Doris!
9.6.24 - The Baca Lab receives the Wong Family Award in Translational Oncology
8.17.24 - Medha presents her work on nucleosome positioning signatures in cfDNA at Cold Spring Harbor.
6.25.24 - Talal and Karl's manuscript on epigenomic profiling of sarcomatoid RCC is published in Cell Reports.
4.8.24 - Welcome Ze!
4.4.24 - Welcome Gary!
3.15.24 - Congrats to Dr. Renee-Maria Saliby who matched in Internal Medicine at Yale!
1.12.24 - The Baca Lab receives the Dana-Farber Cancer Institute Medical Oncology Discovery Award
12.13.23 - Congrats to Jesslyn on a masterful masters thesis defense!
10.21.23 - New epigenomic liquid biopsy assay presented at ESMO and published in Nature Medicine
10.13.23 - Sylvan talks about role of liquid biopsy in precision medicine at the POET Congress in Calgary, AB
9.18.23 - Welcome, Alexis, Medha, and Chris!
7.20.23 - The Baca Lab receives the Damon Runyon Clinical Investigator Award
7.13.23 - Sylvan discusses liquid biopsy in Kidney Cancer at KCRS23
6.25.23 - Karl presents his and Talal's work on the sarcomatoid RCC epigenomics at AACR
6.13.23 - The Baca Lab receives an award to study fragmentomics from the Fund for Innovation in Cancer Informatics
5.25.23 - Abstract on transcriptional regulators of sarcomatoid differentiation accepted for the 2023 Kidney Cancer Research Summit
5.1.23 - Welcome Paulo!
4.2.23 - Karl and Talal's abstract on epigenomic profiling of sarcomatoid RCC is accepted at AACR: Advances in Kidney Cancer Research
2.9.23 - The Baca Lab receives the Young Physician-Scientist Award from the American Society of Clinical Investigation (ASCI)
2.27.23 - Welcome Shahab!
1.30.23 - Welcome Karl!
1.21.23 - Comparative epigenomics of kidney cancer subtypes
9.26.22 - Welcome David!
9.7.22 - Genetic determinants of chromatin reveal mechanisms of inherited prostate cancer risk
8.20.22 - Officially moved into the new space at 375 Longwood Ave
8.16.22 - Distinct Androgen Receptor binding profiles in prostate cancer among African American men
8.5.22 - Ziwei's abstract on polygenic risk scores in lung cancer accepted at ASHG
7.16.22 - Welcome Ziwei!
2.18.25 - Rashad receives an ASCO Merit Award for his ASCO GU25 poster on HIF2α activity and sarcomatoid differentiation in RCC
10.25.24 - The Baca Lab receives the Prostate Cancer Foundation / American Cancer Society Young Investigator Award
10.22.24 - Welcome to rotating HMS PhD students Chris, Harlan, and Doris!
9.6.24 - The Baca Lab receives the Wong Family Award in Translational Oncology
8.17.24 - Medha presents her work on nucleosome positioning signatures in cfDNA at Cold Spring Harbor.
6.25.24 - Talal and Karl's manuscript on epigenomic profiling of sarcomatoid RCC is published in Cell Reports.
4.8.24 - Welcome Ze!
4.4.24 - Welcome Gary!
3.15.24 - Congrats to Dr. Renee-Maria Saliby who matched in Internal Medicine at Yale!
1.12.24 - The Baca Lab receives the Dana-Farber Cancer Institute Medical Oncology Discovery Award
12.13.23 - Congrats to Jesslyn on a masterful masters thesis defense!
10.21.23 - New epigenomic liquid biopsy assay presented at ESMO and published in Nature Medicine
10.13.23 - Sylvan talks about role of liquid biopsy in precision medicine at the POET Congress in Calgary, AB
9.18.23 - Welcome, Alexis, Medha, and Chris!
7.20.23 - The Baca Lab receives the Damon Runyon Clinical Investigator Award
7.13.23 - Sylvan discusses liquid biopsy in Kidney Cancer at KCRS23
6.25.23 - Karl presents his and Talal's work on the sarcomatoid RCC epigenomics at AACR
6.13.23 - The Baca Lab receives an award to study fragmentomics from the Fund for Innovation in Cancer Informatics
5.25.23 - Abstract on transcriptional regulators of sarcomatoid differentiation accepted for the 2023 Kidney Cancer Research Summit
5.1.23 - Welcome Paulo!
4.2.23 - Karl and Talal's abstract on epigenomic profiling of sarcomatoid RCC is accepted at AACR: Advances in Kidney Cancer Research
2.9.23 - The Baca Lab receives the Young Physician-Scientist Award from the American Society of Clinical Investigation (ASCI)
2.27.23 - Welcome Shahab!
1.30.23 - Welcome Karl!
1.21.23 - Comparative epigenomics of kidney cancer subtypes
9.26.22 - Welcome David!
9.7.22 - Genetic determinants of chromatin reveal mechanisms of inherited prostate cancer risk
8.20.22 - Officially moved into the new space at 375 Longwood Ave
8.16.22 - Distinct Androgen Receptor binding profiles in prostate cancer among African American men
8.5.22 - Ziwei's abstract on polygenic risk scores in lung cancer accepted at ASHG
7.16.22 - Welcome Ziwei!