Acupuncture

Research at the Bao Lab

The Bao Lab focuses on investigating integrative medicine approaches to alleviate chemotherapy-induced peripheral neuropathy (CIPN), one of the most common and challenging treatment-related toxicities in cancer care. Our goal is to expand the role of integrative medicine and strengthen the evidence base guiding the incorporation of complementary therapies into conventional oncology practice, particularly for conditions that remain poorly managed.

We are currently conducting two phase III randomized controlled trials to evaluate the efficacy and mechanisms of integrative therapies for chemotherapy-induced peripheral neuropathy (CIPN). The first, supported by an NCI R37 grant, investigates acupuncture for the treatment of CIPN pain in cancer survivors. The second, funded by an NIH R01 grant, examines yoga as an intervention to reduce CIPN symptoms and lower fall risk. Both trials are expected to conclude in 2025 and have the potential to inform and transform clinical practice.

In addition, two feasibility studies are set to begin enrolling participants in early 2026. One will assess Tai Chi for the management of CIPN in cancer survivors, and the other will evaluate the combined use of acupuncture and exercise to address CIPN symptoms in urothelial cancer patients receiving EV-Pembro therapy. Together, these studies aim to advance our understanding of the mechanisms and feasibility of integrative medicine approaches and to help move the field forward.

 

Current Research Studies