Buhrlage Lab News
2024
November
- Ariana presented at the BCMP Data Club. Great job!
- The Buhrlage Lab attended the yearly BCMP Departmental Retreat, returning again to Bretton Woods, NH! Binita, and Isabella gave poster. Gracyn presented a poster and gave a lightning talk! The lab dressed up as PACMAN (wakka wakka wakka) for the annual costume contest.
September
- Matt Knotts, a graduate student in the SSQB Program, has joined the lab. Excited to have you!
August
- Mia Chung, a graduate student in the Chemical Biology Program, has started rotating. Welcome!
July
- Wei Pin is leaving us for a position at AstraZeneca. We will miss you!
June
- Binita presented at the BCMP Data Club. Great job!
- Isabella was awarded a 2024 Fellowship from the Jean Strouse Sharf and the Lisa Sharf Green Cancer Research Fund. Congrats!
May
- The Buhrlage Lab had a great time at the Dana-Farber Cancer Institute Chemical Biology retreat in Cape Cod! Binita gave a poster, and Nick and Isabella gave short talks. Isabella was awarded "Most Informative" speaker, and the Lab won the "Turtle" award at the Build-a-boat competition!
- Ariana presented at the Dana-Farber Cancer Biology Data club. Great job!
- Maria is leaving the lab to pursue her PhD in Chemistry and Chemical Biology at UCSF. Best of luck!
April
- Gracyn has joined the lab. Welcome!
- Sara's earlier work on mutant BRAF contributed to the newly FDA-approved tovorafevid for the treatment of pediatric low-grade gliomas. Congrats Sara on this amazing accomplishment! Read more about it here and here.
January
- Gracyn Mose and Olivia Lavidor, both graduate students in the Chemical Biology Program, have started rotating. Welcome!
2023
December
- Mona Sharafi is leaving us for a position at Amgen. We will miss you!
- Isabella presented at the BCMP Data Club. Great job!
November
- The Buhrlage Lab attended the yearly BCMP Departmental Retreat in beautiful Bretton Woods, New Hampshire! Sara gave a presentation. Isabella and Binita gave a posters, and Binita additionally presented a flash talk. The lab dressed up at Star Wars characters for the annual costume contest (check out the gallery for a picture!).
October
- Sean Gao, a graduate student in the Chemical Biology Program, has started rotating. Welcome!
- Larry Shue, a graduate student in the Biological & Biomedical Sciences PhD Program, has started rotating. Welcome!
September
- Mike Darnowski joins us as a post-doctoral fellow! Welcome to the lab!
- Nick presented at the Cancer Biology Data Club. Great job!
- Congratulations to Dr. Anthony Ayala for successfully defending his thesis!
August
- Sara presented at the Gordon Research Conference for High Throughput Chemistry and Chemical Biology in New Hampshire!
- Esteban and Erick have finished their summer programs and are sadly leaving the lab. It was great to have you both!
July
- Nick presented at the Cancer Chemical Biology & Metabolism Retreat, and Mona volunteered as the program announcer.
- Andres Salazar-Chaparro joins us as a post-doctoral fellow! Welcome to the lab!
- Erick presented a poster at the 2023 Leadership Alliance National Symposium. Great job!
June
- Congrats to Indrajit for publishing his review "Proteomic approaches to study ubiquitinomics" in BBA - Gene Regulatory Mechanisms!
- Esteban Tarazona Guzman has joined the Buhrlage Lab as a summer undergraduate researcher!
- Ujwal is leaving the lab to pursue his PhD in Cell & Molecular Biology at UT Austin. Best of luck!
May
- The Buhrlage Lab attended the first annual Dana-Farber Chemical Biology retreat in Cape Cod! Mona, Nick, and Binita presented their research as short talks. Isabella and Maria gave posters. Great work everyone!
- Erick Gonzalez, a SHURP undergraduate researcher, has joined the Buhrlage Lab for the summer!
- Binita was awarded the National Institute of Health F31 Fellowship! Congrats, Binita!
April
- Indrajit Sahu was accepted to an assistant professor position at SRM-Institute of Science & Technology in Chennai, India. Best of luck starting your lab! We will miss you!
March
- Sara gave a seminar at the Koch Institute for Integrative Cancer Research. Great job!
- Sara presented at the American Chemical Society (ACS) Spring 2023 Meeting in Indianapolis!
February
- Congrats to Adrian for publishing his paper "Accelerating inhibitor discovery for deubiquitinating enzymes" in Nature Communications!
January
- Isabella presented her research at the Chemical Biology Program Data Club. Great job!
2022
December
- Mona presented her research at the BCMP departmental Data Club. Great job!
November
- Idris Barakat, a graduate student in the Chemistry and Chemical Biology PhD program, has started rotating. Welcome!
October
- Sara presented at the Biological Chemistry and Molecular Pharmacology departmental Mini-Retreat.
- Ariana presented her research at the Chemical Biology Program Data Club. Great job!
- Emily Zhang, a graduate student in the Chemistry and Chemical Biology PhD program, has started rotating. Welcome!
September
- Anthony Varca is leaving us for a position at Jnana Therapeutics. We will miss you!
- HyoJeon Kim, a graduate student in the Chemical Biology PhD program, has started rotating as a joint student with the Marto lab. Welcome!
- Yanran is leaving the lab for a position at AstraZeneca. Best of luck!
- Georgia Dittemore, a graduate student in the Chemical Biology PhD program, has started rotating. Welcome!
June
- Congrats to Isabella for passing her qualifying exam and becoming a PhD candidate!
- Cara is leaving the lab to pursue her PhD in Chemistry at Stanford University. Best of luck!
- Ujwal Punyamurtula has joined us as a joint lab technician with the Marto Lab. Welcome, Ujwal!
May
- Congratulations to Dr. Anthony Varca for successfully defending his thesis!
- Maria Tarazona Guzman has joined us as a lab technician. Welcome, Maria!
- Cara and Isabella presented posters at the Biological Chemistry and Molecular Pharmacology departmental retreat.
April
- Wei Pin published a highlight in Molecular Cell titled DUB to the rescue. Check it out!
March
- The Buhrlage Lab, as part of the Center for Emergent Drug Targets, has received a grant from the Massachusetts Life Science Center. Thank you!
- Congrats to Nick for passing his qualifying exam and becoming a PhD candidate!
- Anthony A. presented his research at the BCMP departmental Data Club. Great job!
February
- Congrats to Binita for passing her qualifying exam and becoming a PhD candidate!
- Indrajit Sahu has joined us as a joint postdoctoral researcher with the Marto Lab, welcome!
- Nick was awarded the Chleck Family Fellowship! Congrats!
January
- Congratulations to Dr. Adrian Chan for successfully defending his thesis! He is moving onto a position in industry, all the best!
- Our work on the inhibition of JOSD1 in leukemias with mutant JAK2 was published Leukemia!
2021
December
- Congrats to Anthony Varca for publishing his protocol for high-throughput screening for DUB inhibitors in STAR Protocols!
September
- Congratulations to Sara for earning the title of Associate Professor!
- We received an MPN Challenge Grant from the MPN Research Foundation! Thank you for the support!
- Xiaoxi is leaving the lab for a position in industry! Thank you for all your work building up the foundation of this lab, and all the best in your future endeavors!
- Mona was awarded an NCI-T32 Fellowship. Congrats!
August
- Isabella joined our lab! Welcome back, for the second time!
- Alex is leaving the lab to become a young adult fiction author! Send us copies of your book!!!
- Yanran Lu has joined us as a postdoctoral researcher, welcome!
- Binita has joined as a joint student with the Fischer lab. Welcome!
- Congrats Adrian for publishing his chemoproteomic methods for covalent drug discovery in Chemical Society Reviews!
July
- Congratulations to Dr. Laura Doherty for successfully defending her thesis! Laura will soon be moving to a research scientist position at the Broad Institute.
- Wei Pin Teh has joined as a postdoctoral researcher, welcome!
- Nick, a graduate student from the Biological and Biomedical Sciences PhD program, has joined as a joint student with the Marto lab! Welcome!
June
- Our high-throughput screen in collaboration with the FAST lab at the Novartis Institutes for BioMedical Research is published in Cell Chemical Biology! Congratulations to Anthony Varca!
- Our review article on using selective inhibitors to investigate DUB biological function is published in Cell Chemical Biology! Congratulations Rob!
May
- Rob is leaving us for an Associate Scientific Director position at The Mark Foundation for Cancer Research! All the best, and we look forward to working together in your new capacity.
April
- Mona Sharafi has joined as a postdoctoral researcher, welcome!
- Anthony A. was awarded an NIH F31 grant. Congrats!
- Binita, a graduate student from the Biological and Biomedical Sciences PhD program, has started rotating. Welcome!
March
- Isabella is back as a rotating graduate student in the Chemical Biology PhD program. Welcome back!
January
- We received funding from the AACR and MPM Transformative Cancer Research Grants Program, thank you for your support!
- Emma Dolen, a graduate student in the Chemical Biology PhD program, has started rotating. Welcome!
2020
October
- Our collaborative study with the Fischer Lab titled "Proteomics-based identification of DUB substrates using selective inhibitors" is out on Cell Chemical Biology. Check it out!
- Jing is leaving us for a PI position at the Hefei Institutes of Physical Science at the Chinese Academy of Sciences! We will miss you!
- Zhenze, a joint postdoctoral fellow with the Marto Lab, has joined our lab. Welcome!
September
- Our project on USP7 inhibitors for Ewing sarcoma has been selected for a Drug Discovery Partnership from the Mark Foundation for Cancer Research! Thank you for the support!
August
- Ariana has joined the Buhrlage Lab! Welcome!
June
- Our R21, co-submitted with Dr. Jarrod Marto, has been funded by the NIH! Thank you for the support!
March
- Ariana Bratt, a graduate student in the Chemical Biology PhD program, has started rotating. Welcome!
February
- Anthony A., a graduate student in the Chemistry and Chemical Biology PhD Program, has joined our lab. Welcome!
- Bin is leaving the lab for a scientist position in Delaware. Good luck!
2019
December
- Our funding from the Ellison Foundation has been renewed. Thank you for the continued support!
September
- Zack, a graduate student in the Chemistry and Chemical Biology PhD Program, has started rotating. Welcome!
August
- Xiaoxi has been promoted to Staff Scientist! Congratulations Xiaoxi!
- Rebekka is leaving us to study medicine at the Geothe University Frankfurt in Germany! All the best!
- Cara Starnbach has joined us as a lab technician. Welcome Cara!
June
- Our R01, co-submitted with Dr. Jarrod Marto, has been funded by the NIH! Thank you for the support!
- Isabella Jaen Maisonet and Ethan DaSilva have joined the lab as summer students! Mathiu is back with us for another summer! Welcome (back)!
May
- Congratulations to Dr. Nathan Schauer for successfully defending his dissertation!
January
- We received an ASPIRE Award from the Mark Foundation for Cancer Research! Thank you for the support!
2018
December
- Alex Felix has joined the Buhrlage Lab! Welcome!
- Our funding from the Ellison foundation has been renewed! Thanks for the continued support!
November
- Bin Hu, a synthetic chemistry post-doc, has joined the lab. Welcome Bin!
- Alex Felix, a graduate student in the Chemistry and Chemical Biology PhD Program, has started rotating. Welcome!
October
- Drew Dates, a graduate student in the Chemical Biology PhD Program, has started rotating. Welcome!
June
- Exciting news! We received funding from the Gabrielle’s Angel Foundation for Cancer Research!
- Adrian Chan has joined the lab as a joint student with the Marto Lab! Welcome!
January
- Rebekka has joined the lab as a research technician! Welcome Rebekka!
2017
December
- Our funding from the Ellison foundation has been renewed! Thanks for the continued support!
October
- We received funding from the MPN Research Foundation! Thanks for the support!
September
- Good news! Our grant from the Leukemia and Lymphoma Society has been renewed. Thank you!
- Adrian, a graduate student in the Chemical Biology PhD Program has started rotating. Welcome!
July
- We received funding from the Claudia Adams Barr Program in Innovative Basic Cancer Research at the Dana-Farber Cancer Institute! Thank you!
- Anthony Varca has joined the lab as a graduate student in the Chemical Biology PhD Program. Welcome!
2016
December
- Our R01 on USP7 has been funded! Thank you NIH!
- Our funding from the Ellison foundation has been renewed! Thanks for the continued support!
July
- More good funding news! We received a Dana-Farber Cancer Institute-NU Joint Program Award! Thank you for the support Dana-Farber Cancer Institute and NU!!
June
- Good news! We received a LLS New Ideas Award. Thank you LLS!!
- Welcome Tatiana Mikhailova!! She is joining us for the summer from Berea College.
- Laura Doherty, a graduate student in the Chemical Biology Ph.D. program, has joined our lab. Welcome!!
March
- Laura Doherty received an NSF Graduate Student Fellowship. Congratulations and great job!!
February
- Congratulations to Sara and her husband Chris on the birth of Elise Liu!!
January
- Moving day!! The new lab space is gorgeous! Thank you Gray lab and Structure Core for sharing your space with us for the past several months.
- Xiaoxi Liu, a synthetic chemistry post-doc, has joined the lab. Very excited to get going on chemistry!!
2015
December
- Good news! We received funding from the Ellison Foundation! Thank you Ellison Foundation!
November
- The lab is growing. Welcome Jing Yang!
October
- A warm welcome to Ilaria Lamberto, the first post-doc to join the lab!
September
- Good news! We received a Dana-Farber Accelerator grant. Thank you ORTV for the support!
- Laura Doherty, a graduate student in the Harvard Chemical Biology Ph.D. program, is rotating. Welcome!!
July
- Nathan Schauer, a graduate student in the Harvard Chemical Biology Ph.D. program, has joined the lab. Welcome!!
June
- More good funding news! We received a Dana-Farber Barr grant.
May
- Good news! We received a Dana-Farber Medical Oncology Translation grant.