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News at the Cancelas Lab

July 2026 - New reviwe ! "CD137 in cancer therapy – bench to bedside" Immunotherapy. PMID: 42427082.

Mai 2026 - New review ! "Bone Marrow Stem Cell Connexins: Misconceptions and New Insights" Blood. PMID: 42095943.

April 2026 - New review ! "Unveiling karyoskeletal dynamics in chromatin organization and gene regulation in haematopoietic cell physiology and pathology" Open Biol. PMID: 42014056.

February 2026 - We are proud to share that Dr. Parash Prasad has been selected as a recipient of the 2026 New Investigator Award (NIA) from the American Society for Transplantation and Cellular Therapy (ASTCT). Congratulations!

February 2026 - New review ! "Beyond autologous ex vivo CAR-expressing cell therapies: Toward allogeneic and nucleated cell-free delivery systems of CAR" Molecular therapy oncology. PMID: 41783358.

January 2026 - New review ! "Recharging cellular immunotherapy - targeting immunometabolic aging" Immunotherapy. PMID: 41496735.

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December 2025 - Dr. Prasad has a poster presentation at The 67th ASH Annual Meeting and received an ASH Abstract Achievement Award. Bone marrow microenvironment retinoic acid receptor signaling represses multipotential progenitor dependent B cell lymphopoiesis through secretion of resistin. Abstract

November 2025 - New paper ! "Metabolic adaptation of regenerative hematopoiesis depends on docking-independent mitochondrial connexin 43" Blood. PMID: 40749168.
A commentary of this article by Larry L. Luchsinger published in the same issue "“Connexin” the dots in hematopoietic stem cell potential". PMID: 41196622 and is selected for the Volume 146, Issue 19 cover page.

October 2025 - New review ! "Redox Control in Platelet Activity and Therapy" Antioxidants. PMID: 41300443.

September 2025 - Dr. Cancelas has been honored with the 14th Annual Mentor-of-the-Year Award by the Postdoctoral and Graduate Student Association (PGA) for his outstanding mentorship and dedication. Congratulations!

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September 2025 - New editorial comment ! "Freeze-Dried Platelet-Derived Hemostatic Products to Treat Bleeding in Dual Antiplatelet Therapy" JACC: Basic to Translational Science. PMID: 40992829.

December 2024 - Dr. Prasad has an oral presentation at The 66th ASH Annual Meeting. Bone marrow adipocyte secreted resistin is a positive regulator of long-term hematopoietic stem cell engraftment and myelopoiesis. Abstract

November 2024 - New paper ! "G-CSF resistance of ELANE mutant neutropenia depends on SERF1 containing truncated neutrophil elastase aggregates"The Journal of Clinical InvestigationPMID: 39560992

October 2024 - New paper ! "Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets". Blood. PMID: 39088777

July 2024 - Jose Cancelas, MD, PhD, recently joined Dana-Farber Cancer Institute named director the Connell and O'Reilly Families Cell Manipulation Core Facility (CMCF).