Cancelas Lab Publications
- Rallis K, Liegel JJ, Pommier A, Ciuculescu FM, Cancelas JA, Gribben JG and Avigan DE. CD137 in cancer therapy – bench to bedside. Immunotherapy. 2026 July 9:1-17. PubMed
- Rallis K, Singh A and Cancelas JA. Bone Marrow Stem Cell Connexins: Misconceptions and New Insights. Blood. 2026 May 7:blood.2025031836. PubMed
- Kamran M, Nassar N and Cancelas JA. Unveiling karyoskeletal dynamics in chromatin organization and gene regulation in haematopoietic cell physiology and pathology. Open Biol. 2026 Apr 22;16(4):260011. PubMed
- Rallis K, Dionisio LM, Tarannum M, Romee R and Cancelas JA. Beyond autologous ex vivo CAR-expressing cell therapies: Toward allogeneic and nucleated cell-free delivery systems of CAR. Mol Ther Oncol. 2026 Feb12;34(1):201155. PubMed
- Rallis K, Pommier A, Singh A and Cancelas JA. Recharging cellular immunotherapy - targeting imunometabolic aging. Immunotherapy. 2025 Nov;17(16):1155-1156 PubMed
- Singh AK, Angelo D'Alessandro, Ashley M Wellendorf, Daniel Gonzalez-Nieto, Matthew Kofron, Monika Dzieciatkowska, Leo Mejia, Luis C Barrio, Marie-Dominique Filippi, Jose A Cancelas. Metabolic adaptation of regenerative hematopoiesis depends on docking-independent mitochondrial connexin 43. Blood. 2025 Nov 6;146(19):2306-2321 PubMed
- Dionisio LM, Zheng Y and Cancelas JA. Redox Control in Platelet Activity and Therapy. Antioxidants (Basel). 2025 Oct 27;14(11):1286 PubMed
- Dionisio LM and Cancelas JA. Freeze-Dried Platelet-Derived Hemostatic Products to Treat Bleeding in Dual Antiplatelet Therapy. JACC: Basic to Translational Science 2025 Sept 10; 10(9):101374 PubMed
- Parash Prasad, Angelo D'Alessandro, Abhishek K Singh, Yi Zheng, John Manis, Li Chai, Mohd Kamran, Mark Soliman, Ashley M Wellendorf, Leo Mejia, Hongbo R Luo, Sean R Stowell, Shin-Young Park, Martin J Aryee, Mercedes Ricote, Nathan Salomonis, Jose A Cancelas. Bone Marrow Adipokine Mediates Hematopoietic Regeneration and Stem Cell Fitness. BioRxiv 2025 Sep 2:2025.08.28.672647 PubMed
- Hegde S, Akbar H, Wellendorf AM, Nestheide S, Johnson JF, Zhao X, Setchell KD, Zheng Y, Cancelas JA. Inhibition of RHOA activity preserves the survival and hemostasis function of long-term cold-stored platelets. Blood. 2024 Oct 17;144(16):1732-1746. PubMed
- Prasad P, Cancelas JA. From Marrow to Bone and Fat: Exploring the Multifaceted Roles of Leptin Receptor Positive Bone Marrow Mesenchymal Stromal Cells. Cells. 2024 May 24;13(11):910. PubMed
- Nayak RC, Emberesh S, Trump LR, Wellendorf AM, Singh AK, Korkmaz B, Horwitz MS, Myers KC, Kalfa TA, Lutzko CM, Cancelas JA. G-CSF resistance of ELANE-mutant neutropenia depends on SERF1-containing truncated-neutrophil elastase aggregates. J Clin Invest. 2024 Nov 19;135(2):e177342. PubMed
- Singh AK, Prasad P, Cancelas JA. Mesenchymal stromal cells, metabolism, and mitochondrial transfer in bone marrow normal and malignant hematopoiesis. Front Cell Dev Biol 2023; 11:1325291. PubMed
- Hegde S, Zheng Y, Cancelas JA. Novel blood derived hemostatic agents for bleeding therapy and prophylaxis. Curr Opin Hematol 2022; 29:281-289. PubMed
- Nayak RC, Chang KH, Singh AK, Kotliar M, Desai M, Wellendorf AM, Wunderlich M, Bartram J, Mizukawa B, Cuadrado M, Dexheimer P, Barski A, Bustelo XR, Nassar NN, Cancelas JA. Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis. Nat Commun 2022; 13:3056. PubMed
- Serrano-Lopez J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf AM, Roche PA, Rangel Y, Carrington LJ, Geiger H, Grimes HL, Luther S, Maillard I, Sanchez-Garcia J, Starczynowski DT, Cancelas JA. Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics. Elife 2021. PubMed
- Singh AK, Cancelas JA. Mitochondria Transfer in Bone Marrow Hematopoietic Activity. Curr Stem Cell Rep 2021; 7:1-12. PubMed
- Hegde S, Wellendorf AM, Zheng Y, Cancelas JA. Antioxidant prevents clearance of hemostatically competent platelets after long-term cold storage. Transfusion 2021; 61:557-567. PubMed