Remote Intervention Helps Women with Breast Cancer, Obesity Lose Nearly 5% of Body Weight

Dr. Ligibel spoke with Healio about the Breast Cancer Weight Loss (BWEL) trial following her presentation at the San Antonio Breast Cancer Symposium. She shared promising preliminary results indicating that the trial's telephone-based lifestyle intervention did more than just help patients lose weight; it significantly improved critical metabolic and inflammatory biomarkers. Specifically, she noted a ~20% reduction in insulin levels and a 25% improvement in insulin resistance among participants—changes that are mechanistically linked to cancer outcomes. She emphasized that the team is now waiting to see if these favorable biological shifts will translate into the study's primary goal: a reduction in breast cancer recurrence.

Read the full report here: https://www.healio.com/news/hematology-oncology/20250912/remote-intervention-helps-women-with-breast-cancer-obesity-lose-nearly-5-of-body-weight