Lab and Collaborative Articles

Lab and collaborative articles are all Meyerson laboratory publications, as well as publications led by other groups, where a member or members of the Meyerson Laboratory shares authorship.

2025

2024

2023

  • Tarantino, P, Gupta, H, Hughes, ME, Files, J, & ... (2023). Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer. Nature Communications. https://www.nature.com/articles/s41467-023-43324-w
  • Gibson, WJ, … Meyerson, M & ... (2023). Bifunctional small molecules that induce nuclear localization and targeted transcriptional regulation. Journal of the American Chemical Society. https://doi.org/10.1021/jacs.3c06179
  • Aquilanti, E, … & Meyerson, M (2023). Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume. Neuro-Oncology. https://academic.oup.com/neuro-oncology/article-abstract/25/7/1275/7000407
  • Shih, J, & ... (2023). Cancer aneuploidies are shaped primarily by effects on tumour fitness. Nature. https://www.nature.com/articles/s41586-023-06266-3
    Orsi, DL, … Meyerson, M, … & Goldstein, JT (2023). Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as a covalent PPARG inverse-agonists. Bioorganic & Medicinal Chemistry. https://doi.org/10.1016/j.bmc.2022.117130

2022

2021

2020

  • Carrot-Zhang, J, … Berger, AC, … Cherniack, AD, & … (2020). Comprehensive analysis of genetic ancestry and its molecular correlates in cancer. Cancer Cell. https://www.cell.com/cancer-cell/fulltext/S1535-6108(20)30211-7
  • Nomburg, J, Meyerson, M, & … (2020). Pervasive generation of non-canonical subgenomic RNAs by SARS-CoV-2. Genome Medicine. https://doi.org/10.1186/s13073-020-00802-w
  • Llabata, P, Mitsuishi, Y, …, Meyerson, M & ... (2020). Multi-omics analysis identifies MGA as a negative regulator of the MYC pathway in lung adenocarcinoma. Molecular Cancer Research. https://aacrjournals.org/mcr/article-abstract/18/4/574/90118
  • Zhang, Z, … & Meyerson, M (2020). Patterns of chromosome 18 loss of heterozygosity in multifocal ileal neuroendocrine tumors. Genes Chromosomes & Cancer. https://doi.org/10.1002/gcc.22850
  • Lamberti, G, Spurr, LF, … Meyerson, M, Cherniack, AD, & … (2020). Clinicopathological and genomic correlates of programmed cell death ligand 1 (PD-L1) expression in nonsquamous non-small-cell lung cancer. Annals of Oncology. https://doi.org/10.1016/j.annonc.2020.02.017
  • Nomburg, J, … Meyerson, M, & … (2020). Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm. Blood. https://doi.org/10.1182/bloodadvances.2019001260
  • Touat, M, Li, YY, … Cherniack, AD, & … (2020). Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. https://doi.org/10.1038/s41586-020-2209-9 
    Wu, X, … Cherniack, AD, … Meyerson, M, & Greulich, H (2020). Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.RA119.011191

2019

2018

2017

2016

2015

2014

  • Berger, AH, … & Meyerson, M (2014). Oncogenic RIT1 mutations in lung adenocarcinoma. Oncogene. https://doi.org/10.1038/onc.2013.581
  • Bhatt, AS, … Meyerson, M, & … (2014). Brief Report: In Search of a Candidate Pathogen for Giant Cell Arteritis: Sequencing-Based Characterization of the Giant Cell Arteritis Microbiome. Arthritis & Rheumatology. https://doi.org/10.1002/art.38631
  • Choi, PS, & Meyerson, M (2014). Targeted genomic rearrangements using CRISPR/Cas technology. Nature communications. https://www.nature.com/articles/ncomms4728
    The Cancer Genome Atlas Research Network, Meyerson, M, & … (2014). Comprehensive molecular profiling of lung adenocarcinoma. Nature. https://doi.org/10.1038/nature13385
  • Hoadley, KA, Yau, C, Wolf, DM, Cherniack, AD, … (2014). Multiplatform Analysis of 12 Cancer Types Reveals Molecular Classification within and across Tissues of Origin. Cell. https://doi.org/10.1016/j.cell.2014.06.049
  • Francis, JM, Zhang, CZ, Maire, CL, … Meyerson, M & … (2014). EGFR Variant Heterogeneity in Glioblastoma Resolved through Single-Nucleus Sequencing. Cancer. https://aacrjournals.org/cancerdiscovery/article-abstract/4/8/956/4553
  • Helman, E, Lawrence, MS, Stewart, C, … & Meyerson, M (2014). Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing. Genome. https://genome.cshlp.org/content/24/7/1053.short
  • Brooks, AN, … Meyerson, M, & … (2014). A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events. PloS one. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087361
  • Watanabe, H, Ma, Q, Meyerson, M, & ... (2014). SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas. The Journal of Clinical Investigation. https://www.jci.org/articles/view/71545
  • Pugh, TJ, ... Meyerson, M, & … (2014). Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA …. Oncogene. https://www.nature.com/articles/onc2014150
  • Imielinski, M, Greulich, H, … Meyerson, M, & … (2014). Oncogenic and sorafenib-sensitive ARAF mutations in lung adenocarcinoma. The Journal of Clinical Investigation. https://www.jci.org/articles/view/72763
  • Sharifnia, T, … & Meyerson, M (2014). Genetic modifiers of EGFR dependence in non-small cell lung cancer. PNAS. https://doi.org/10.1073/pnas.1412228112
  • Cho, J, Bass, AJ, … & Meyerson, M (2014). Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive …. Molecular cancer. https://doi.org/10.1186/1476-4598-13-141
  • Partfenov, M, Pedamallu, CS, … Meyerson, M, & … (2013). Characterization of HPV and host genome interactions in primary head and neck cancers. PNAS. https://doi.org/10.1073/pnas.1416074111

2013

2012

2011

2010

2009

  • Bass, AJ, Watanabe, H, … & Meyerson, M (2009). SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nature. https://www.nature.com/articles/ng.465
  • Chiang, DY, Getz, G, … Meyerson, M & … (2009). High-resolution mapping of copy-number alterations with massively parallel sequencing. Nature. https://www.nature.com/articles/nmeth.1276
  • Beroukhim, R, … Meyerson, M & … (2009). Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney. Cancer …, aacrjournals.org, https://aacrjournals.org/cancerres/article-abstract/69/11/4674/549656
  • Rozenblatt-Rosen, O, … & Meyerson, M (2009). The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3′ mRNA processing factors. PNAS.https://doi.org/10.1073/pnas.0812023106
  • Ramos, AH, … & Meyerson, M (2009). Amplification of chromosomal segment 4q12 in non-small cell lung cancer. Cancer biology & …, Taylor & Francis, https://doi.org/10.4161/cbt.8.21.9764

2008

  • The Cancer Genome Atlas Research Network, Meyerson, M, … (2008). Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. https://doi.org/10.1038/nature07385
  • Ding, L, … Meyerson, M, & … (2008). Somatic mutations affect key pathways in lung adenocarcinoma. Nature. https://doi.org/10.1038/nature07423
  • Dutt, A, … Meyerson, M, & Greulich, H (2008). Drug-sensitive FGFR2 mutations in endometrial carcinoma. PNAS. https://doi.org/10.1073/pnas.0803379105
  • George, RE, … Greulich, H, … Meyerson, M, & … (2008). Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature, nature.com, https://www.nature.com/articles/nature07397
  • Chiang, DY, … Meyerson, M, & … (2008). Focal Gains of VEGFA and Molecular Classification of Hepatocellular Carcinoma. Cancer …, aacrjournals.org, https://aacrjournals.org/cancerres/article-abstract/68/16/6779/540746
  • Li, C, … & Meyerson, M (2008). Major copy proportion analysis of tumor samples using SNP arrays. BMC …, Springer, https://doi.org/10.1186/1471-2105-9-204
    2007
  • Weir, BA, … & Meyerson, M (2007). Characterizing the cancer genome in lung adenocarcinoma. Nature. https://doi.org/10.1038/nature06358  
  • Thomas, RK, … Meyerson, M, & ... (2007). High-throughput oncogene mutation profiling in human cancer. Nature. https://www.nature.com/articles/ng1975
  • Minami, Y … Meyerson, M, & Thomas, RK (2007). The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272. Oncogene, nature.com, https://www.nature.com/articles/1210292
  • Yuza, Y, … & Meyerson, M (2007). Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors. Cancer biology & …, Taylor &Francis, https://doi.org/10.4161/cbt.6.5.4003

2006

  • Lee, JC, … Meyerson, M, & … (2006). Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS …, journals.plos.org, https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0030485
  • Hayes, DN, … & Meyerson, M (2006). Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts. Journal of Clinical …, ascopubs.org, https://doi.org/10.1200/JCO.2005.05.1748
  • Thomas, RK, … & Meyerson, M (2006). Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing. Nature Medicine. https://doi.org/10.1038/nm1437
  • Ji, H, Zhao, X, … Meyerson, M & … (2006). Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors. PNAS.https://doi.org/10.1073/pnas.0510284103
  • MacConaill, LE, … & Meyerson, M (2006). Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583. Molecular cancer …, aacrjournals.org, https://aacrjournals.org/mcr/article-abstract/4/10/793/232728

2005

2004

2000-2003

Pre-2000