Hanghui Ye

EDUCATION

PhD, Genetics & Epigenetics, MD Anderson UTHealth Houston Graduate School, Houston, TX, USA 

BS, Biosciences, University of Science and Technology of China, Hefei, Anhui, China

SELECTED PUBLICATIONS

Ye H*, McDonald TO*, Elghaish R, Sei E, Conterno Minussi D, Hu M, Bai S, Tang C, Wang J, Wang K, Downey RJ, Casasent A, Nicholson MD, Chen H, Michor F, Navin NE. A pan-cancer single-cell analysis of intratumoral copy number diversity and evolution. Cancer Discov. 2026 Jun 8. doi: 10.1158/2159-8290.CD-25-0964. Epub ahead of print. PMID: 42258702.

Wang J*, Minussi DC*, Davis A*, Wei R, Ye H, Sei E, Schalck A, Yan Y, Wu HJ, Bai S, Peng C, Hu M, Casasent A, Contreras A, Chen H, Hui D, Damodaran S, Edgerton ME, Kopetz S, Lim B, Navin N. Delineating the copy-number substructure of metastatic tumors with CopyKit. Mol Cell. 2026 Jan 22;86(2):407-422.e6. doi: 10.1016/j.molcel.2025.12.026. Epub 2026 Jan 13. PMID: 41534520. 

Minussi DC*, Nicholson MD*, Ye H*, Davis A, Wang K, Baker T, Tarabichi M, Sei E, Du H, Rabbani M, Peng C, Hu M, Bai S, Lin YW, Schalck A, Multani A, Ma J, McDonald TO, Casasent A, Barrera A, Chen H, Lim B, Arun B, Meric-Bernstam F, Van Loo P, Michor F, Navin NE. Breast tumours maintain a reservoir of subclonal diversity during expansion. Nature. 2021 Apr;592(7853):302-308. doi: 10.1038/s41586-021-03357-x. Epub 2021 Mar 24. PMID: 33762732; PMCID: PMC8049101.

Wang G*, Chow RD*, Bai Z, Zhu L, Errami Y, Dai X, Dong MB, Ye L, Zhang X, Renauer PA, Park JJ, Shen L, Ye H, Fuchs CS, Chen S. Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity. Nat Immunol. 2019 Nov;20(11):1494-1505. doi: 10.1038/s41590-019-0500-4. Epub 2019 Oct 14. PMID: 31611701; PMCID: PMC6858551.

Codina A*, Renauer PA*, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Syst. 2019 Feb 27;8(2):136-151.e7. doi: 10.1016/j.cels.2019.01.004. Epub 2019 Feb 20. PMID: 30797773; PMCID: PMC6592847.

*Co-first authors

SELECTED AWARDS

Postdoctoral fellowship, National Cancer Center (2026-2027)

Andrew Sowell-Wade Huggins Fellowship in Cancer Research (2021-2024)

Andrew Sowell-Wade Huggins Scholarship in Cancer Research (2024)

T.C. Hsu Memorial Scholarship (2022)