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​Polyak Laboratory for Breast Cancer Research 

 

“In questions of science, the authority of a thousand is not worth the humble reasoning of a single individual.”

— Galileo Galilei, physicist and astronomer (1564–1642)

Welcome to the Polyak Lab

Dedicated to the molecular analysis of human breast cancer.

Our goals:

  • Better understand the molecular evolution of human breast tumors
  • Use this knowledge to improve the clinical management of breast cancer patients

What's New

Whole-genome doubling drives immune evasion by silencing antigen presentation

Pierre Foidart ∙ Zheqi Li ∙ Xinran Cai

Identification of cycling regulatory T cell precursors as conductors of immune escape during breast carcinoma progression

Triet M. Bui

HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies

Marie-Anne Goyette