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​Polyak Laboratory for Breast Cancer Research 

 

“In questions of science, the authority of a thousand is not worth the humble reasoning of a single individual.”

— Galileo Galilei, physicist and astronomer (1564–1642)

Welcome to the Polyak Lab

Dedicated to the molecular analysis of human breast cancer.

Our goals:

  • Better understand the molecular evolution of human breast tumors
  • Use this knowledge to improve the clinical management of breast cancer patients

What's New

Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response

Zheqi Li

Breast cancer prevention by prophylactic Lalba mRNA-LNP vaccination
Breast cancer prevention by prophylactic Lalba mRNA-LNP vaccination

Jun Nishida

Whole-genome doubling drives immune evasion by silencing antigen presentation

Pierre Foidart ∙ Zheqi Li ∙ Xinran Cai