Research Highlights
Rewiring the Fusion Oncoprotein EWSR1::FLI1 in Ewing Sarcoma with Bivalent Small Molecules
Bond, Michael J., et al.
Journal of the American Chemical Society - 2025
The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
Malone, Clare F., et al.
Science Advances - 2024
Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia
Schneider, Constanze, et al.
Cancer Research - 2024
DOI: 10.1158/0008-5472.CAN-23-3560
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma
Lu, Diana Y., et al.
Nature Cell Biology - 2023
DOI: 10.1038/s41556-022-01059-8
An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML
Lin, Shan, et al.
Cancer Discovery - 2022
DOI: 10.1158/2159-8290.CD-20-1851
A first-generation pediatric cancer dependency map
Dharia, Neekesh V., et al.
Nature Genetics - 2021
DOI: 10.1038/s41588-021-00819-w
