Duy Nguyen

PhD Student (BBS)

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Hometown: Ho Chi Minh City, Vietnam

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Duy is a graduate student in Biomedical & Biological Sciences (BBS) at The Harvard Kenneth C. Griffin Graduate School of Arts and Sciences. He received his B.A. in Biochemistry and Pre-Medicine at Augustana College. He then worked as a research technician in Dr. Bishoy Faltas’s lab, and subsequently led a multidisciplinary project studying the interplay of mutagenesis and ecDNA in shaping urothelial cancer evolution. In the lab now he is interested in the relationships between oncogenic transcription factors and their associated cofactors.

 

  1. Selected publications: 
  • Nguyen DD*, Hooper WF*, Liu W*, Chu TR, Geiger H, Shelton JM, Shah M, Goldstein ZR, Winterkorn L, Helland A, Sigouros M, Manohar J, Moyer J, Al Assaad M, Semaan A, Cohen S, Madorsky Rowdo F, Wilkes D, Osman M, Singh RR, Sboner A, Valentine HL, Abbosh P, Tagawa ST, Nanus DM, Nauseef JT, Sternberg CN, Molina AM, Scherr D, Inghirami G, Mosquera JM, Elemento O, Robine N, Faltas BM. The Interplay of Mutagenesis and ecDNA Shapes Urothelial Cancer Evolution. Nature. Doi: 10.1038/s41586-024-07955-3. 

  • Liu W, Newhall KP, Khani F, Barlow LM, Nguyen D, Gu L, Eng K, Bhinder B, Uppal M, Récapet C, Sboner A, Ross SR, Elemento O, Chelico L, Faltas BM. The cytidine deaminase APOBEC3G drives cancer mutagenesis and clonal evolution in bladder cancer. Cancer Research. 2022, 83 (4): 506–520. PMID: 36480186. Doi: 10.1158/0008-5472.CAN-22-2912. 

  • Ohara K, Figueiredo Rendeiro A, Bhinder B, Eng KW, Ravichandran H, Nguyen D, Pisapia D, Vosoughi A, Fernandez E, Shohdy KS, Manohar J, Beg S, Wilkes D, Robinson BD, Khani F, Bareja R, Tagawa ST, Sboner A, Elemento O, Faltas BM, Mosquera JM. The evolution of metastatic upper tract urothelial carcinoma through genomic-transcriptomic and single-cell protein markers analysis. Nature Communications. 2024, 15(1):2009. PMID: 38499531. Doi: 10.1038/s41467-024-46320-w. 

    *equal contribution