Valerie Nguyen

Valerie Tú Uyên Nguyen is a graduate student in Biomedical & Biological Sciences (BBS) at Harvard University. She earned a B.S. in Biology and a B.A. in American Studies with a Chemistry minor (with Honors) from the University of North Carolina at Chapel Hill, where she was a Carolina Scholar (full merit scholarship). At UNC Lineberger Comprehensive Cancer Center, she trained in Dr. Ian Davis’s lab, studying chromatin regulation and genome-wide sequencing in Ewing sarcoma and completing an honors thesis focused on chromatin accessibility modulation. Prior to starting her PhD, she was a Fulbright Research Fellow at the Princess Máxima Center in Utrecht in Dr. van Heesch’s lab, combining wet-lab and computational approaches (including ribosome profiling) to study microproteins in Ewing sarcoma. She then joined Duke University Medical Center as a DIRECT Research Fellow in Dr. Graves and Somarelli’s lab, where she investigated bioenergetic vulnerabilities in chemotherapy-resistant osteosarcoma.

Selected Publications: 

1. Vital T, Wali A, Butler KV, Xiong Y, Foster JP 2nd, Marcel SS, McFadden AW, Nguyen VU, Bailey BM, Lamb KN, James LI, Frye SV, Mosely AL, Jin J, Pattenden SG, Davis IJ. MS0621, a novel small-molecule modulator of Ewing sarcoma chromatin accessibility, interacts with an RNA-associated macromolecular complex and influences RNA splicing. Front Oncol. 2023;13:1099550. Doi: 10.3389/fonc.2023.1099550.